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: zVAD-inhibited insulin secretion inside the existence of significant glucose medium, but this end result wasn't significant as opposed to Manage islets (10 EP3 and EP4 receptors have the best affinity for PGE2 and usually few to Gαs signaling pathways. Then again, EP1 receptors pair to Gαq signaling pathway, stimulating PLC activity intraneuron

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